- 1 Tampa Bay Buccaneers vs Cleveland Browns: four turnovers on one side, five sacks on the other
- 2 Tampa Bay Buccaneers: a ball-security problem, not a scoring problem
- 3 Cleveland Browns: an offensive line in free fall
- 4 NFL Prediction Tampa Bay Buccaneers vs Cleveland Browns
- 5 First, a word on our free picks
- 6 No commitment from us
- 7 Information changes
- 8 Your responsibility
- 9 Responsible gambling first
- 10 Legal age
- 11 About the visuals…
Tampa Bay Buccaneers vs Cleveland Browns: four turnovers on one side, five sacks on the other 
Tampa Bay coughed up four turnovers and took four sacks in its season opener in Cincinnati. Baker Mayfield alone lost three fumbles in the 33-27 defeat.
Cleveland had a different kind of nightmare, just as damaging: a 34-10 loss to Jacksonville, with Deshaun Watson sacked five times. The Browns’ only touchdown came late, against backups.
So both teams sit at 0-1, undone by problems in different areas. Tampa gave the ball away. Cleveland never kept it long enough.
The game is at Raymond James Stadium on Sunday, September 20 at 1:00 p.m. ET.
The market makes the Tampa Bay Buccaneers eight-point favorites, with the total set at around 40.5. That points to a tight, one-sided game rather than an offensive shootout.
One stat stands out above the rest: Cleveland is 4-14 against the spread on the road since 2024. No other team in the league has been worse over that span.
There is also a personal angle. Mayfield faces the team that made him the No. 1 pick in the draft, and he has never been one to treat that lightly.
The two teams do not meet often, with schedules rarely lining up in recent years. That leaves the focus on individual storylines rather than any real shared history.
The total around 40.5 tells you most of what to expect. Few observers think Cleveland can score enough to turn this into a track meet.
For Tampa Bay, this is about protecting its early-season credibility. A second straight loss, this time at home, would leave the Buccaneers in an awkward spot heading into the rest of the schedule.
Tampa Bay Buccaneers: a ball-security problem, not a scoring problem 
The Buccaneers scored 27 points at Paycor Stadium despite four turnovers. Any offense that can put up that kind of number while sabotaging itself is still dangerous once it cleans up the mistakes.
Mayfield’s three fumbles are the core issue. A quarterback who puts the ball on the ground three times in one game almost never repeats that line the next week.
The defense, for its part, gave up 33 points in Cincinnati, a worrying number after a promising preseason. It had been billed as Tampa’s top offseason project.
Going home changes plenty. The Buccaneers get back their offensive rhythm and a noisy building that makes life harder for visiting lines.
Mayfield also signed a September extension worth $165 million, making him the franchise’s long-term face. That kind of status does not usually lead to caution in the playbook.
Rookie Rueben Bain Jr. hurt his shoulder in August during a joint practice with Jacksonville, though the early outlook was positive. His availability still needs monitoring for the defensive rotation.
The defensive line also lost Vita Vea in a messy situation, after he requested a trade in late July as camp got underway. Eight seasons of continuity in the middle do not get replaced in a few weeks.
That helps explain part of the 33 points allowed in Cincinnati. Against a much more limited Cleveland attack, Tampa has the perfect chance to settle itself down.
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Cleveland Browns: an offensive line in free fall 
Five sacks on Deshaun Watson in Week 1. That number explains almost everything about the 34-10 loss to Jacksonville.
Watson had not played a regular-season game since 2024 before Sunday. Todd Monken still named him starter once the season began, because there was no credible alternative.
That lack of options got worse in late August when Dillon Gabriel landed on injured reserve. The rookie had just produced his best preseason outing, going 12-for-15 with three touchdowns against the Patriots.
The run game no longer covers for anything since Nick Chubb retired at 30 in August. Cleveland lost its historic offensive anchor in one offseason.
The trip to Florida does not help a record that is already ugly: 4-14 against the spread on the road since 2024. The Browns have not been covering away from home, no matter the opponent.
Against a Tampa defense that will be desperate to respond in front of its own crowd, Watson’s protection is once again the main issue. A line that gave up five sacks last week offers very little confidence here.
Cleveland has also been dealing with discipline issues in the trenches, with Tytus Howard fined $12,537 in early September for a tripping incident in practice. It says plenty about the mood around that offensive line.
Todd Monken now has to piece together a game plan with shaky protection and no realistic backup plan at quarterback. His room for error keeps shrinking every week.
NFL Prediction Tampa Bay Buccaneers vs Cleveland Browns
Our pick: Tampa Bay Buccaneers -7.5
Simulation models give Tampa Bay a win probability of more than 75%, with a commonly projected final score of 27-13. A straight Buccaneers win pays too little to be worth it, so the spread is the play.
Cleveland comes in with an offensive line that was beaten five times in one game, no reliable run threat and the worst road spread record in the league over the last two seasons. Tampa Bay is back home after scoring 27 points despite four turnovers, and Mayfield is unlikely to repeat that kind of mess.
A seven-and-a-half-point margin fits this setup comfortably. The Buccaneers cover at Raymond James Stadium.
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