Cleveland Browns vs Buffalo Bills - Free NFL prediction and tips - December 21, 2025

Cleveland Browns vs Buffalo Bills – Free NFL prediction and tips – December 21, 2025

Match context Cleveland Browns vs Buffalo Bills National Football League - Wikipedia

A lop-sided bill on paper. Buffalo are still hunting a division crown. Cleveland are already thinking draft picks. The Bills come off a statement win in New England, erasing a 17-point deficit to steal the result and stay in the AFC East race.

Cleveland, meanwhile, are in free fall. At 3–11 the Browns just took a pasting in Chicago (31–3). The offense can’t string together two clean drives. Their only real target now is individual: let Myles Garrett chase the NFL sack record.

Keys to the Cleveland Browns vs Buffalo Bills clash Cleveland Browns vs Buffalo Bills

The offensive gap is massive. Buffalo have the league’s best ground game and Josh Allen — capable of flipping a game on his own. They don’t need perfection. A steady run plan, short fields and mistakes from Cleveland will do the rest.

Cleveland will cling defensively, thanks to Garrett. But reality’s blunt: the offense isn’t helping. Shedeur Sanders struggles past basic reads, the run game is invisible and every drive looks like a fight to nick 15 yards. If Buffalo grabs an early lead, it’ll become a rout of control.

Bouton PenseBet

Free Pick Cleveland Browns vs Buffalo Bills

Result : Buffalo Bills -10,5

Buffalo don’t need a monster day to cover. Play it smart: run the ball, take few risks, and the better team will make Cleveland crack. The Browns will limit damage in patches. They don’t have the legs to hang for 60 minutes.

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