- 1 Liverpool vs Atletico de Madrid: two starts to the season that have little in common
- 2 Liverpool look to back up their first win of the season
- 3 Atletico de Madrid arrive off their first defeat of the season
- 4 Football Prediction Liverpool vs Atletico de Madrid
- 5 Before anything else, a word on our free predictions
- 6 No commitment from us
- 7 Information changes
- 8 Your responsibility
- 9 Responsible gambling first
- 10 Legal age
- 11 About the images…
Liverpool vs Atletico de Madrid: two starts to the season that have little in common 
Liverpool head into their first European night with five points from three Premier League games. Atletico de Madrid have seven after four La Liga matches.
The gap in the table is clear enough, but it hides something more revealing: the Reds claimed their first win on September 4, while Atletico suffered their first defeat on September 5 in Bilbao.
Two 2-2 draws, away at St James’ Park and then at Anfield against Nottingham Forest, kicked off Liverpool’s season. Matchday three finally brought a 2-0 win over Ipswich Town, taking them to five points overall.
Atletico’s first setback of the campaign came on Friday September 5, when they were beaten 0-3 in Bilbao on matchday four of La Liga.
The Colchoneros had started with two wins and a draw in three games, scoring seven and conceding three, before that collapse at San Mames.
The league phase format gives every club eight matches against eight different opponents. Slip up early and the overall standings bite back fast.
The draw spread 144 matches across those eight rounds. None of the 36 teams got the same hand as the side next to them.
Anfield opens the league phase with a heavyweight tie, with Atletico dented by the weekend and the Reds back in the win column.
The league phase begins on Wednesday September 9 at Anfield, with kick-off set for 20:00 UK time, which is 21:00 in France.
These two clubs know each other well on the European stage. Liverpool have won three of the last five Champions League meetings between the sides.
The latest came on September 17, 2025, a 3-2 win for the Reds at Anfield. That is the most useful recent reference point for what awaits on Wednesday.
The league form adds a little noise to the picture. Liverpool got their first win on September 4, beating Ipswich 2-0, while Atletico took their first loss in Bilbao on September 5, going down 0-3.
The two squads are broadly comparable in quality, which takes some of the shine off those early season tune-up games.
Anfield remains one of the toughest grounds in Europe to visit, and that matters more than any table in early September.
Liverpool look to back up their first win of the season 
Two 2-2 draws to start, then a 2-0 win over Ipswich Town in matchday three: Liverpool have collected five points from three outings. The defensive picture is improving, even if the four goals conceded in the first two matches still linger in the memory.
Four goals shipped in two games is twice as many as Manchester City conceded over the same spell. Arsenal, by contrast, have let in just one goal in three matches.
The draw at St James’ Park was rescued by a Dominik Szoboszlai penalty in the 99th minute after Cody Gakpo had struck.
That kind of game tells you two things at once. This side keeps going right to the end, but it also makes life harder than it should for itself before the hour mark.
The second draw, at home to Nottingham Forest, only sharpened the concern. Anfield was not enough to turn territorial control into three points.
The 2-0 win over Ipswich Town on September 4 finally got the season moving. Anfield now has a victory backdrop again before Atletico arrive.
Five points from three games puts Liverpool back in the top half of the English table.
One small wrinkle on the first two matches: the Reds were the only Premier League side to draw both of their opening games. That is no longer the case.
European nights often change this club’s mood completely. The 3-2 win against the same opponent a year ago is the clearest example.
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Atletico de Madrid arrive off their first defeat of the season 
Seven points from a possible 12 after four games: Atletico suffered their first setback on September 5, beaten 0-3 in Bilbao. Their display at San Mames raised eyebrows, especially from a defence that had only conceded three goals up to that point.
After three matches, seven scored and three conceded had Atletico sitting third in Spain, behind Barcelona and Real Madrid.
The key detail for Wednesday is their away record. A 3-1 win on the road in La Liga, then a heavy 0-3 loss in Bilbao: away from the Metropolitano, the picture is all over the place.
Julian Alvarez was one of the summer’s big talking points at the club. Arsenal and Barcelona both pushed for the Argentina striker, but neither could prise him away.
Keeping him changes the outlook for Diego Simeone. The Argentine coach still has his main attacking focal point for a full European campaign.
The defeat in Bilbao forces Simeone to tidy up a few defensive details before Anfield. Atletico’s centre-back pairing were breached three times without reply.
Atletico’s draw and defeat came in very different settings. A home draw, then a 0-3 away loss: that volatility on the road is the first thing to read into this trip.
Seven goals in four La Liga matches still put Atletico’s attack among the best in Spain, behind only Barcelona and Real Madrid.
The memory of Anfield still matters. Atletico lost 3-2 there in September 2025, in the most recent meeting between the clubs.
Kicking off the league phase with a trip to England is no easy assignment, and the Bilbao defeat adds a little more heat on Atletico’s shoulders.
Probable Liverpool line-up: Not available at time of publication.
Probable Atletico de Madrid line-up: Not available at time of publication.
Football Prediction Liverpool vs Atletico de Madrid
Our prediction: both teams to score
Liverpool have scored and conceded in both of their first two Premier League games. The 2-0 win over Ipswich settled the defensive look a bit, but four goals conceded in the opening two outings still matter.
Atletico have scored seven in four La Liga matches but have also given up six, including three at once in Bilbao. A defence that can unravel on the road and an attack that keeps producing: that points to a lively contest.
The last meeting between these two at Anfield finished 3-2, with five goals and both teams on the scoresheet.
Both attacks are working, and both defences have already shown cracks away from home. Both teams to score looks the play, no drama.
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