San Francisco 49ers vs Chicago Bears – Free NFL prediction and picks – December 28, 2025

San Francisco 49ers vs Chicago Bears – Free NFL prediction and picks – December 28, 2025

San Francisco 49ers vs Chicago Bears: contenders’ showdown under pressure in Santa Clara National Football League — Wikipédia

Sunday Night Football hands us a proper NFC stress test. Chicago and San Francisco wear the same record, the same hunger, and both are pointing toward January. At Levi’s Stadium this is more than a regular-season win: it’s seeding, swagger and credibility on the line against an equal opponent.

Bears: a team that refuses to die Chicago Bears - Wikipedia

Chicago shows up with something few teams still have this late in the year: total belief they can flip any script. The Bears have proved time and again no deficit is too big. The recent win over Green Bay only cemented that identity. Caleb Williams hasn’t been flawless, but he’s been calm, decisive and dangerous when the game got tight.

Offensively, Chicago’s balanced enough to hang in any matchup. The run does the dirty work, protection holds up, and Williams now has enough weapons to punish defenses that overplay. It won’t steamroll opponents. It grinds. Possession after possession.

Defensively, it’s messy at times, especially versus the run, but the Bears make up for it by forcing mistakes. Turnovers aren’t an extra—they’re a weapon. In a close game, that flips the scoreboard.

49ers: winning despite the wear File:San Francisco 49ers logo.svg - Wikimedia Commons

San Francisco keeps racking up wins, but there’s no safety net. Injuries are stacking, especially on defense, and the margin’s thinner. Result: fewer highlight plays, more discipline. The 49ers have to be clean, chew the clock and milk drives instead of living off splash plays.

Brock Purdy plays without fear and stays deadly efficient when the system clicks. Christian McCaffrey is still the offense’s linchpin—he controls tempo and eases the QB’s load. The doubt around George Kittle matters. If he’s out, Chicago can attack the middle differently.

At home the 49ers still have a structural edge. But the coverage is starting to show cracks and the pass rush doesn’t inspire the same fear. Against a team that never panics, that’s risky.

Reading the matchup

The script’s obvious: San Francisco will try to control the ball and grind Chicago down with the run. The Bears will take the slugfest and wait for chances. The longer it stays tight, the more the psychological edge slides to Chicago — they’ve already shown they win in chaos.

The high total fits both teams’ offensive upside and their defensive holes. Long offensive series, late adjustments and forced errors could turn this into an open game.

Clés du match San Francisco 49ers File:San Francisco 49ers logo.svg - Wikimedia Commons vs Chicago Bears Chicago Bears - Wikipedia

The health of San Francisco’s key players. Every absence hits hard against an opportunistic team.

Turnover management. Chicago lives off those moments.

The fourth quarter. If the Bears are still in it with ten minutes left, the pressure flips to San Francisco.

Free NFL pick San Francisco 49ers File:San Francisco 49ers logo.svg - Wikimedia Commons vs Chicago Bears Chicago Bears - Wikipedia

Over 50.5 points. Very tight duel, value on the Bears.

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