Indianapolis Colts vs Jacksonville Jaguars - Free NFL Prediction and Picks - December 28, 2025

Indianapolis Colts vs Jacksonville Jaguars – Free NFL Prediction and Picks – December 28, 2025

Match context Indianapolis Colts vs Jacksonville Jaguars  National Football League — Wikipédia

The Colts are out. This AFC South clash comes at a crunch time for both teams, but momentum couldn’t be more different. Jacksonville has already punched its playoff ticket, riding six straight wins and a solid road win in Denver last week. Still, the Jaguars aren’t free of pressure — Houston sits just one win behind in the division race.

The Colts were knocked out without even playing for it — a heavy home loss to San Francisco, and the Texans’ win yesterday, did the damage.

Key things to watch Indianapolis Colts Indianapolis Colts - Wikipedia vs Jacksonville Jaguars Jacksonville Jaguars - Wikipedia

The main factor is the emotional and situational context. Jacksonville’s red-hot and already locked into the playoffs. That’s exactly the kind of spot where a team can ease off the gas, consciously or not.

Across from them, Indianapolis will want to finish the season on a high. Philip Rivers is into his third game since coming back and he’s starting to show progress — better reads, better tempo control. With Jonathan Taylor chasing the league rushing title, expect the Colts to lean on the run and chew clock.

Free NFL prediction Indianapolis Colts vs Jacksonville Jaguars

Under 48.5 total points in the game.

Recent form clearly favors Jacksonville, but the context makes you look past the favourite. The Colts, in front of their home crowd, won’t just lie down.

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