Seattle Seahawks vs San Francisco 49ers - Free NFL Prediction and Picks - January 17, 2026

Seattle Seahawks vs San Francisco 49ers – Free NFL Prediction and Picks – January 17, 2026

Seattle Seahawks – San Francisco 49ers: Home team huge favorites? NFL

The NFC meets at Lumen Field. Seattle, the conference’s best in the regular season, hosts the 49ers they’re all too familiar with. A divisional playoff clash is never routine, and this one looks a lot tighter than the standings suggest.

Seattle: continuity is their biggest weapon Seattle Seahawks

Seattle crept forward quietly, but with impressive consistency. A 14–3 record, an NFC West title and the conference’s top seed: hard to top that. At home the Seahawks went up another gear, backed by a crowd that turns Lumen Field into a roaring pressure cooker.

The offense is the main engine here. Sam Darnold is putting together the best season of his NFL career. Clean, disciplined, efficient — he’s made the system work for him. His connection with Jaxon Smith-Njigba has upgraded Seattle’s passing game, capable of striking fast and hard whenever a window opens.

With a week’s rest to prepare, the Seahawks arrive fresh, organised and fully aware that home crowd advantage still matters big time at this stage.

San Francisco: travel doesn’t faze them Fichier:San Francisco 49ers logo.svg — Wikipédia

San Francisco turn up as underdogs, but not patsies. Sixth seed at 12–5, the 49ers built their season away from home with an eye-catching 8–2 road record. Their 23–19 win in Philly in the Wild Card underlined they can stay solid in hostile environments.

Brock Purdy keeps the ship steady and calm. He doesn’t chase flash — he manages, distributes and avoids mistakes. But the real heartbeat of this attack is Christian McCaffrey. Runner, receiver, mismatch-creator — he’s the anchor of the California game plan.

Leaning on him to control the clock and disrupt the opponent’s rhythm, the 49ers will try to blunt Seattle’s pressure and keep the game in a constant state of threat.

Keys to the game

  • Seattle finished the regular season with the best record in the NFC.
  • The Seahawks are solid at home, fuelled by the Lumen Field atmosphere.
  • San Francisco has an excellent road record this season (8–2).
  • Christian McCaffrey remains the 49ers’ number one weapon to control the tempo.
  • San Francisco has won seven of the last nine meetings with Seattle.


Bouton PenseBet

NFL Prediction Seattle Seahawks vs San Francisco 49ers

Seattle Seahawks to win

Seattle deserve the favourite tag, especially at home where their offence finds its rhythm more easily. That said, this won’t be comfortable. The 49ers know how to bother the Seahawks and stay in it until the final whistle. In a tight, tense game the home advantage and offensive consistency should still tip the balance towards Seattle.

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